Hepatosplenomegaly

Multiple myeloma with hepatosplenomegaly.

1Assistant Professor, Internal Medicine; 2Assistant Professor, Pathology; 3Head of Department of Critical Care; Military Hospital, Trivandrum Received: 22.07.2011; Accepted: 10.08.2013 Sir, T e C a s e r e p o r t “ M u l t i p l e m y e l o m a p r e s e n t i n g w i t h hepatosplenomagaly”1 was interesting and we would l ike to o f fer these comments 1. Peripheral blood smear giving a clue t...

An Unusual Case of Hepatosplenomegaly

An Unusual Case of Hepatosplenomegaly with Cytopenia

Autoimmune lymphoproliferative syndrome (ALPS) is a rare, inherited disorder of immune dysregulation secondary to defective lymphocyte apoptosis. This leads to uninhibited proliferation of lymphoid tissue manifesting with lymphadenopathy, hepatosplenomegaly, autoimmune cytopenia, and an increased risk of lymphoid malignancy. We report a twoyearold boy with fever, generalized lymphadenopathy, he...

Cytomegalovirus Infection in Infants with Hepatosplenomegaly

Cytomegalovirus (CMV) infection is the most common congenital infection with the incidence varying from 1% to 3%. At birth, approximately 10% of intrauterine infected infants demonstrate clinical symptoms and signs of infection which carries a risk of morbidity and mortality. Perinatal infection occurs in the contact of an infant with secretions and excretions of the mother with active CMV infe...

An Aetiological study of hepatosplenomegaly in adults

This is a randomized hospital-based study of fifty cases from either sex-all above the age of twelve years. There were 41 (82%) male and 9 (18%) female patients. 52% of cases belong to low income group and 48% hail from middle class. Occupations of the patients were cultivation (26%), service (24%), studentship (20%), housewife (i 4%) and business (10%). The study shows malignant disorders of h...